the current methods for treatment of cancers are inadequate and more specific methods such as gene therapy are in progress. among different vehicles, cationic liposomes are frequently used for delivery of genetic material. this investigation aims to prepare and optimize dotap cationic liposomes containing an antisense oligonuclotide (asodn) against protein kinase c alpha in non-small cells lung...

Objective(s): The aim of present study is to formulate mefenamic acid transdermal gel based on vesicular drug delivery approaches.Materials and Methods: For the preparation of mefenamic acid transdermal gel, transfersomes were selected as colloidal carriers. Transfersomes were prepared by hand shaking and thin film hydration techniques. The obtained transfersomes were characterized for vesicula...

Objective(s): The purpose of the present study was to prepare and to evaluate a novel niosome as transdermal drug delivery system for propranolol hydrochloride and to compare the in vitro efficiency of niosome by either thin film hydration or hand shaking method. Materials and Methods: Niosomes were prepared by Thin Film Hydration (TFH) or Hand Shaking (HS) method. Propranolol niosomes were pre...

objective(s): the purpose of the present study was to prepare and to evaluate a novel niosome as transdermal drug delivery system for propranolol hydrochloride and to compare the in vitro efficiency of niosome by either thin film hydration or hand shaking method. materials and methods: niosomes were prepared by thin film hydration (tfh) or hand shaking (hs) method. propranolol niosomes were pre...

The current methods for treatment of cancers are inadequate and more specific methods such as gene therapy are in progress. Among different vehicles, cationic liposomes are frequently used for delivery of genetic material. This investigation aims to prepare and optimize DOTAP cationic liposomes containing an antisense oligonuclotide (AsODN) against protein kinase C alpha in non-small cells lung...

The current methods for treatment of cancers are inadequate and more specific methods such as gene therapy are in progress. Among different vehicles, cationic liposomes are frequently used for delivery of genetic material. This investigation aims to prepare and optimize DOTAP cationic liposomes containing an antisense oligonuclotide (AsODN) against protein kinase C alpha in non-small cells lung...

       Cyproterone acetate (CA) has been loaded to liposome by solvent evaporation and thin film formation technique. The effects of some formulation variables such as temperature of organic solvent evaporation, rotary evaporator speed, volume of organic solvent, volume of balloon and temperature of hydrating buffer has been evaluated. The data showed that bigger balloon with higher surface are...

This paper describes a methodology that realizes an array of heterologous giant liposomes with gentle hydration. The system consists of an array of micropores on a thin polymer film, which is overlaid on a pair of comb ITO-electrodes. An electrospray deposition (ESD) method allows selective lipid patterning of green and red fluorescent-labeled lipids at the micropores that expose either of the ...

cyproterone acetate (ca) has been loaded to liposome by solvent evaporation and thin film formation technique. the effects of some formulation variables such as temperature of organic solvent evaporation, rotary evaporator speed, volume of organic solvent, volume of balloon and temperature of hydrating buffer has been evaluated. the data showed that bigger balloon with higher surface area has b...

The aim and objective of the study was to develop herbal drug loaded niosomes as topical gel by using thin film hydration technique. The practicability of herbal drug (CODE: THDC3-2615RD) of niosomes by thin film hydration technique using Span series 20, 60, 80 and cholesterol has been successfully revealed in this study. The evolved herbal niosomes were evaluated for morphology, particle size ...